Nasolabial Folds (Smile Lines): Treatment Options
An honest guide to nasolabial folds, the lines from the nose to the mouth: why they deepen, how filler and supporting treatments soften them, and what to expect.

Nasolabial folds, often called smile lines or laugh lines, are the lines that run from the sides of the nose to the corners of the mouth. They typically deepen with age as the face loses volume and collagen, and can be softened with dermal filler and supporting treatments, decided at a consultation.
What nasolabial folds are, and why they deepen
Everyone has nasolabial folds to some degree, even in youth, because they sit where the cheek meets the upper lip and move every time you smile or speak. They become more noticeable over time, and several things contribute at once. The main reason is ageing: the face gradually loses volume in the midface, while collagen and elastin, the proteins that keep skin firm and springy, decline. As the cheek loses support, the tissue above the fold descends slightly, and the line looks deeper.
Skin laxity, genetics, and years of sun exposure all play a part, as does the natural way your face is structured. This is worth saying plainly: deepening smile lines are a normal feature of a face that moves and ages, not a flaw. The aim of treatment is to soften them so they sit in better balance with the rest of your face, not to erase them completely.
How nasolabial folds can be treated
Dermal filler is the main treatment. The important point, and one that surprises people, is that the most natural result often comes from placing filler in the cheek and midface to restore support, rather than injecting only into the fold itself. Treating the cause, a loss of volume higher up, tends to lift and soften the line more naturally than filling the crease directly, which can look heavy if overdone. In some cases a small, careful amount in the fold is still appropriate, decided on how your face looks at rest and in movement.
Filler is not the only piece. Skin-quality and regenerative options such as Profhilo, skin boosters and polynucleotides, can improve the firmness and texture of the skin itself, and non-surgical lifting can address laxity for the fuller picture. A good plan is bespoke and considers the whole midface, rather than applying one fixed approach to every face.
Who it suits, and realistic results
Good candidates are people whose folds have deepened mainly through volume loss and who want a softer, more rested look while keeping natural movement. Realistic results matter here more than almost anywhere else on the face. Softening typically means the shadow is reduced and the area looks smoother and better supported, not that the line vanishes. Over-filling the fold is the classic mistake: it can create a heavy, unnatural ridge beside the mouth and often makes the area look worse rather than better. A measured, whole-face approach gives the most natural outcome.
What to expect
Treatment begins with an assessment of the whole midface, not just the line that caught your eye in the mirror. Your clinician looks at your cheeks, your skin quality, and how your face moves, then explains what is likely to help and what is not. The treatment itself involves injecting a hyaluronic acid filler, usually with a fine needle or a cannula, and most people find it very manageable, helped by numbing where needed. There is often some swelling or minor bruising for a few days.
Results are visible quickly and settle over about two weeks. How long they last varies with the product, the area and your own metabolism, but midface filler typically lasts from several months to longer, and top-ups maintain the result over time. Because hyaluronic acid filler is broken down gradually by the body, the effect is temporary and repeatable.
Safety, risks and aftercare
Dermal filler is a medical treatment with real, if mostly uncommon, risks. The usual short-term effects are bruising, swelling and tenderness, and occasionally small lumps that can be smoothed or that settle with time. The most serious risk, though rare, is vascular: filler affecting a blood vessel. The area around the nose and mouth has an important blood supply, which is exactly why who treats you matters so much. An experienced medical injector understands the anatomy, works to reduce this risk, and knows how to manage a complication should one occur.
Aftercare is straightforward: keep the area clean, avoid heavy exercise, alcohol, and very hot environments for a day or so, and avoid pressing or massaging the area unless you are told otherwise. A reassuring feature of hyaluronic acid filler is that it can be dissolved if you are unhappy with a result or in the rare event of a complication, which is part of responsible practice.
The Beauty Script’s approach
Our approach to smile lines is assessment-first and whole-face. We look at why the folds have deepened and treat the cause, often supporting the midface rather than simply filling the line, and we recommend only what will genuinely help. You can read more about our dermal filler treatments and how facial areas work together. Care is led by a registered nurse prescriber. The clinic is Save Face accredited and JCCP registered, treatments are carried out in CQC-regulated premises, and our team is trained in aesthetic complications. There is never any pressure to proceed.
Questions
Frequently asked questions
They are caused mainly by ageing. The midface gradually loses volume, and collagen and elastin decline, so the cheek loses support and the line from the nose to the mouth looks deeper. Skin laxity, genetics, sun exposure and your natural facial structure all contribute. Everyone has these folds to some degree.
Not usually, and trying to erase them often looks unnatural. The realistic goal is softening: reducing the shadow and restoring support so the area looks smoother and more rested while keeping natural movement. A line that is completely flattened tends to look overdone, so a measured, whole-face approach gives the best result.
Often the cheek, which surprises people. Because the folds deepen as the midface loses volume, restoring support higher up can lift and soften the line more naturally than filling the crease directly. In some cases a small, careful amount in the fold itself is appropriate too. Your clinician decides based on your face at rest and in movement.
It varies with the product, the area treated and your own metabolism. Midface filler typically lasts from several months to longer, and top-ups maintain the result over time. Because hyaluronic acid filler is broken down gradually by the body, the effect is temporary and repeatable rather than permanent.
Most people find it very manageable. A fine needle or a cannula is used, and numbing cream or filler containing a local anaesthetic helps with comfort. You may feel some pressure during treatment and have mild swelling or bruising for a few days afterwards, which settles on its own.
Yes, as with any injectable. Common short-term effects are bruising, swelling, tenderness and occasionally small lumps. The most serious risk, though rare, is vascular, where filler affects a blood vessel. This area has an important blood supply, which is why an experienced medical injector who understands the anatomy and can manage complications matters.
There is no single best treatment, because it depends on why the folds have deepened. Dermal filler to support the midface is the usual mainstay, sometimes combined with skin-quality or regenerative treatments, or non-surgical lifting for laxity. A consultation that assesses the whole face decides the right combination for you.
Good skincare and sun protection support skin quality and can slow some of the changes that make folds more noticeable, so they are worth maintaining. On their own, though, they will not replace lost midface volume, so they tend to work best alongside treatment rather than instead of it.
Important
This article is for general information only and is not medical advice. It should not replace a consultation with a qualified medical practitioner. Treatments described here are only suitable following an in-person assessment, and results vary between individuals. Always seek personalised clinical advice before deciding on any treatment.
Key takeaways
- Nasolabial folds are the lines that run from the sides of the nose to the corners of the mouth.
- They deepen with age as the face loses volume, collagen and elasticity, and everyone has them to some degree.
- Dermal filler is the main treatment, often placed in the cheek to support the area rather than only in the fold.
- Skin-quality and regenerative options, and non-surgical lifting, can form part of the fuller picture.
- The goal is softening, not erasing, and over-filling the fold looks unnatural.
- A consultation that assesses the whole midface decides what, if anything, suits you.

Written by
Valentina Pakhrutdinova
Registered Nurse Prescriber (NMC), Aesthetic Complications Expert
Valentina is the founder and lead practitioner of The Beauty Script. A registered nurse prescriber with a background in emergency and intensive care nursing, she takes an anatomy-led, consultation-first approach and treats only what will genuinely make a difference. She is Save Face accredited, JCCP registered, and an Aesthetic Complications Expert.
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