The Hair

Hair Loss Treatments in London: PRP, Polynucleotides and Exosomes

Thinning hair has several causes, and no single treatment suits everyone. Here is an honest look at PRP, polynucleotides and exosomes, and how to choose.

Valentina PakhrutdinovaMedically reviewed by Valentina Pakhrutdinova5 August 20269 min read

Scalp and hair restoration treatment at a London aesthetics clinic

Hair loss treatments in London include PRP, polynucleotides, and the newer area of exosomes, each aiming to support the scalp and the hair follicles rather than promising to reverse hair loss outright. Which one suits you depends on the cause of your thinning, your general health, and what is realistic, so an honest assessment comes first. The goal of these treatments is to support the hair environment, and results vary between individuals.

Understanding hair loss first

Before any treatment, it is worth understanding that hair loss is not one condition. It can be driven by genetics, hormones, stress, nutrition, thyroid or iron levels, and other medical factors, often in combination. Two people with thinning hair can need very different approaches, and some causes are best managed medically rather than with an in-clinic treatment.

This is why a responsible clinic asks about your health and, where appropriate, suggests blood tests or a referral before recommending a treatment. Treating the scalp without understanding the cause is unlikely to give a lasting result.

PRP for hair

PRP, or platelet-rich plasma, uses a small sample of your own blood. It is processed to concentrate the platelets, then injected into the scalp, where the growth factors it contains support circulation and the health of the follicles. Because it uses your own blood, nothing synthetic is added. Our PRP hair restoration treatment is usually delivered as a course, with improvement building over the months that follow.

Polynucleotides for hair

Polynucleotides are regenerative injectables, often derived from purified salmon DNA fragments, that support tissue repair and the scalp environment. Used on the scalp, they aim to improve the conditions in which hair grows. Interest in polynucleotides for the scalp is growing, and you can read more about how the treatment works in our full polynucleotides guide. As with PRP, the evidence continues to develop, and it is not a guaranteed route to regrowth.

Exosomes for hair

Exosomes are one of the newest areas in regenerative aesthetics. They are tiny vesicles that cells use to carry signals, and the interest is in their potential to support repair. It is important to be measured here. This is an emerging field, the evidence is still developing, and the regulatory position is evolving. Any clinic discussing exosomes should be honest that this is a newer area rather than a proven, guaranteed solution, and should explain the current status openly at consultation.

PRP, polynucleotides and exosomes compared

Treatment	What it is	How it is viewed
PRP	Your own concentrated platelets, injected into the scalp	Well established in aesthetic practice, delivered as a course
Polynucleotides	Regenerative injectables that support the scalp environment	A growing area, evidence still developing
Exosomes	Cell-derived signalling vesicles	An emerging area, evidence and regulation still evolving

A general comparison of the three treatments. All support the hair environment rather than guaranteeing regrowth.

None of these is a guaranteed cure, and they are often most useful as part of a wider plan rather than in isolation. For many people, the right approach combines an in-clinic treatment with attention to the underlying cause of their hair loss.

What to expect and realistic results

Hair changes slowly, so these treatments are usually given as a course and judged over months, not days. Many people notice reduced shedding first, before any change in density. Because the hair cycle is gradual, patience and consistency matter, and your clinician will set out a realistic timeline for you. Where a treatment is unlikely to help your particular type of hair loss, an honest clinic will tell you so rather than proceed.

Comfort, downtime and safety

These are injectable treatments, so mild scalp tenderness, redness, or the occasional small bruise can occur and usually settle within a day or two. As with any medical treatment there are small risks, which are discussed at consultation. Treatment should only be carried out by a qualified medical practitioner who has assessed your suitability.

Hair loss treatment at The Beauty Script

Our approach is medically-led and honest. We assess the likely cause of your hair loss first, recommend only what is genuinely appropriate, and are clear about what each treatment can and cannot do. Care is led by a registered nurse prescriber. The clinic is Save Face accredited and JCCP registered, and treatments are carried out in CQC-regulated premises. If you are concerned about thinning hair and would like a realistic opinion, a consultation is the right first step.

Questions

Frequently asked questions

In-clinic options include PRP, which uses your own concentrated platelets, and polynucleotides, a regenerative injectable that supports the scalp. Exosomes are a newer, emerging area. These support the hair environment rather than guaranteeing regrowth, and the right choice depends on the cause of your hair loss, which should be assessed first.

PRP can support the follicles and the scalp environment using growth factors from your own blood, and many people have it as a course for thinning hair. It is not a guaranteed cure, and it suits some types of hair loss better than others. An assessment of the cause of your thinning helps set realistic expectations.

Polynucleotides are used on the scalp to support the environment in which hair grows, and interest in this use is growing. The evidence is still developing, so it is not a guaranteed route to regrowth and is not suitable for every type of hair loss. A proper assessment should always come first.

Exosomes are one of the newest areas in regenerative aesthetics. The evidence is still developing and the regulatory position is evolving, so they should be discussed honestly as an emerging option rather than a proven, guaranteed treatment. A responsible clinic will explain the current status openly.

Hair changes slowly, so these treatments are given as a course and judged over months rather than days. Many people notice reduced shedding before any change in density. Because the hair cycle is gradual, patience and consistency matter, and your clinician will give you a realistic timeline.

There is no single best option. The right choice depends on the cause of your hair loss, your health, and what is realistic, which is why an assessment comes first. For many people the best approach combines an in-clinic treatment with attention to the underlying cause.

Sometimes, yes. Because hair loss can be linked to hormones, thyroid, iron, and other medical factors, a responsible clinic may suggest blood tests or a referral before recommending a treatment. Understanding the cause makes any treatment more likely to help.

Most people tolerate it well. Mild scalp tenderness, redness, or a small bruise can occur and usually settle within a day or two. Comfort measures are used, and your clinician will talk you through what to expect and the small risks involved at your consultation.

Important

This article is for general information only and is not medical advice. It should not replace a consultation with a qualified medical practitioner. Treatments described here are only suitable following an in-person assessment, and results vary between individuals. Always seek personalised clinical advice before deciding on any treatment.

Key takeaways

Hair loss has several causes, so assessing the cause comes before choosing a treatment.
PRP uses your own blood to deliver growth factors that support the follicles.
Polynucleotides are regenerative injectables that support the scalp environment.
Exosomes are an emerging area with evolving evidence, and are not a guaranteed solution.
These treatments support the hair environment rather than promising regrowth.
A consultation and, where needed, a medical work-up decide what is appropriate.

Written by

Valentina Pakhrutdinova

Registered Nurse Prescriber (NMC), Aesthetic Complications Expert

Valentina is the founder and lead practitioner of The Beauty Script. A registered nurse prescriber with a background in emergency and intensive care nursing, she takes an anatomy-led, consultation-first approach and treats only what will genuinely make a difference. She is Save Face accredited, JCCP registered, and an Aesthetic Complications Expert.

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